Metagenomics for Rapid Pathogen Detection and Characterization of the Microbiome in Health and Disease

Metagenomics for Rapid Pathogen Detection and Characterization of the Microbiome in Health and Disease

Next-gen sequencing, combined with high-resolution metagenomic analysis, offers a new powerful method for diagnosis of infectious diseases. We applied this in several clinical studies, including a retrospective case control study comprising samples of known and unknown etiology, as well as samples from healthy individuals. The results are promising and demonstrate that microbiome analysis could potentially differentiate healthy, diseased, and asymptomatic carriers, including individuals in the early stages of infection and disease.